By J.K. Aronson (Eds.)
The uncomfortable side effects of gear Annual is designed to supply a severe and updated account of latest info with regards to antagonistic drug reactions and interactions from the clinician's viewpoint. below the supervision of the sequence editors, a world crew of professional authors have accumulated jointly the newest details on hostile drug results from the overseas literature. as well as describing new reviews of inauspicious drug results, the authors have subjected these reviews to severe research, environment them into context when it comes to medical relevance and significance, and cross-referring to prior stories the place worthy. New opposed results are mentioned and evaluated and formerly said antagonistic results are re-evaluated within the mild of the newest details. a distinct characteristic is the stories, within which chosen antagonistic results are mentioned extensive. using the e-book is more desirable by means of separate indexes, permitting the reader to go into the textual content through drug identify, antagonistic impression identify, or drug interplay. the present Annual is the 1st replace of the normal encyclopaedic paintings during this box, http://www.elsevier.nl/locate/isbn/0444500936Meyler's unintended effects of gear, Fourteenth variation, which used to be released in December 2000.
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Extra info for A world-wide survey of new data and trends in adverse drug reactions
J Heart Valve Dis 1999; 8: 232. 44. Jefferson HG, Jayne DR. Peripheral vasculopathy and nephropathy in association with phentermine. Nephrol Dial Transplant 1999; 14: 1761-3. 45. Korkmaz C, Fresko I, Yazici H. A case of systemic sclerosis that developed under dexfenfluramine use. Rheumatology 1999; 38: 379-80. 46. Aeschiimann A, Truchis P, Khan MF. Scleroderma after therapy with appetite suppressants. Scand J Rheumatol 1990; 19: 88-9. 47. Sobel RM. Ruptured retroperitoneal aneurysm in a patient taking phentermine hydrochloride.
Weissman NJ. Appetite suppressant valvulopathy: a review of current data. Cardiovasc Rev Rep 1999; 20: 146-55. 34. Adams C, Cohen A. Appetite-suppressant drugs and heart abnormalities. Arch Mal Coeur Vaiss 1999; 92: 1213-19. 35. Ewalenko M, Richard CL, Vandenbossche JL. Fenfluramine and cardiac valvular diseases. Rev Med Brux 1999; 20: 419-26. 36. Kancheda MK, Salti HI, Mulderink TA, Parker M, Bonow RO, Mehlman DJ. Echocardiographic prevalence of mitral and/or aortic regurgitation in patients exposed to either fenfluraminephentermine combination or to dexfenfluramine.
Fluoxetine increased the plasma area under the curve of reboxetine by 20%, but this was not statistically significant. The authors suggest that the combination of fluoxetine and reboxetine should have minimal adverse impact in depressed patients. However, the major metabolite of fluoxetine, norfluoxetine, is also an inhibitor of CYP3A4 and would not have reached steady-state concentrations during the time of the study. This suggests that caution might still be needed during longerterm use of this combination in depressed patients.
A world-wide survey of new data and trends in adverse drug reactions by J.K. Aronson (Eds.)